Global health threats, from infectious disease outbreaks to complex humanitarian emergency operations, pose significant risks to both national and international security. For Navy Medicine, these threats directly impact the health and readiness of our Sailors and Marines, and the stability of the maritime environments in which we operate. Navy Medicine’s Health Security Cooperation (HSC) efforts are a critical component of the U.S. Navy's strategic readiness and a key element of the whole-of-government approach to global health. These engagements build partner capacity, enhance interoperability, and strengthen relationships with allies and partner nations, directly supporting U.S. national security objectives. This poster abstract will present a series of compelling case studies and best practices from recent Navy Medicine HSC initiatives. It will highlight a range of activities, including joint medical training exercises, subject matter expert exchanges, and collaborative research and development projects. The analysis will focus on how these engagements are designed to address specific health security vulnerabilities in partner nations while simultaneously providing invaluable operational and readiness training for U.S. naval medical forces. Navy Medicine's HSC initiatives have demonstrated a clear and compelling impact on both global health security and our own naval readiness. Through collaborative engagements, there is strengthened ability among our partners to address health challenges, fostering greater resilience within their communities. These interactions also provide invaluable opportunities for U.S. Navy medical teams to sharpen their skills and enhance their preparedness for a wide range of operational environments. Ultimately, our work in this space cultivates trust and builds enduring relationships, creating a foundation for effective collaboration and a shared approach to managing transnational health threats. Navy Medicine’s strategic HSC are not merely humanitarian endeavors; they are force multipliers that are essential to achieving naval superiority and securing a healthier future. By proactively engaging with our international partners, Navy Medicine not only contributes to global health security but also directly enhances the readiness and operational capabilities of our own forces. This poster will demonstrate how a robust HSC program leads the way in preparing federal health professionals to meet the complex challenges of a dynamic global environment, ensuring a more resilient and secure future for all.