Enlisted members have been involved in almost every facet of US military operations since its inception. Likewise, when George Washington’s Continental Army formed the Army and Navy medical services in 1775, provisions were made to detail enlisted personnel to assist the medical officers. Over the years, as the services formed separate medical departments, the roles of the enlisted members have changed, and today, they occupy a diverse range of military occupations in the direct care system as well as Warfighting units. Career senior enlisted members have been on the forefront of change throughout the history of the Military and the Military Health System (MHS). These are the people who have led and guided others through the various iterations of change, failures, and successes. This panel is comprised of individuals who served in senior leader roles within the Military Health System (MHS). They represent the three branches of the military that provide health service support to our Warfighters and Families at home and abroad - Army, Navy, Air Force. These leaders have served in various positions throughout their careers, successfully managed change, are now retired from the military, and have gone on to perform in a variety of new roles. The panel provides a unique perspective on leadership and offers insights into how to best connect people and ideas to achieve success. The panel’s goal is to help current leaders learn from their experiences so they can lead effectively.