The Military Health System (MHS) and Veterans Health Administration (VHA) are two of America’s largest and most complex health care institutions. Together, these two systems provide care to America’s Service members during and after military service. While the missions of the two systems are unique, there are similarities between MHS and VHA patient populations. Consequently, collaborations between the MHS and VHA can enhance patient care, advance evidence-based care into practice, improve access to disability benefits, support innovative problem solving, and enhance the patient experience. The VHA and DoD collaborate with key stakeholders on a rigorous process to develop and update joint clinical practice guidelines (CPGs), conducting literature reviews utilizing standardized assessments and scoring to produce up-to-date recommendations advancing evidence-based care into practice. The overall timeline and process for CPGs includes not only the development or update to the content, but also an external validation process prior to finalization, and then the dissemination of the CPG along with developed clinical support tools. CPGs are used in health care to improve patient care as a potential solution to reduce inappropriate variations in care and to optimize outcomes for Service members, their dependents, retirees, and Veterans. Collaboration between VA and DoD also occurs via the VA/DoD Joint Incentive Fund (JIF), which was created by Congress to encourage shared initiatives and approaches to problem solving that mutually benefit both Departments with the potential to support a variety of opportunities. Prospective JIF projects should be aware of program oversight, the annual funding cycle, project manager responsibilities, and key elements of successful proposals. These components support successful JIF projects that can lead into joint and sustainable programs, such as the Individual Longitudinal Exposure Record (ILER). The ILER provides the DoD and VA the ability to link Service members and Veterans to known exposures, promoting efficient and effective continuity of health care. The ILER is leveraged in support of the PACT Act, recent legislation expanding VA health care and benefits for toxic exposures in service. In addition to supporting continuity of care, this capability supports health effects research, exposure mitigation measures, and the ability for Service members or Veterans to receive disability benefits by removing the beneficiary’s burden of proof and providing a comprehensive record for service exposures. Patient outcomes are benefited through an understanding of an individuals’ health care journey. To promote positive outcomes, as a leader in a customer-centered culture, the VA has created the VA Customer Experience Institute (VACXi) to share and collaborate on insights gained on customer needs, enabling human-centered approaches. Discussion of these solutions, lessons learned, and next steps can help inform DoD approaches to patient-centric care. This breakout session will include presentations on development of VA/DoD CPGs, the VA/DoD JIF with examples of past successful projects, the ILER and implementation of the PACT Act, and the lessons learned through the VACXi to highlight existing and potential opportunities for DoD and VA collaboration.