Abstract Public health deployment refers to the temporary assignment of officers from their regular duties within HHS OPDIVs or HHS STAFFDIVs, and sometimes non-HHS organizations, as authorized by the President or Secretary. This occurs in response to various situations, including times of war, National Health Emergencies declared by the President, Public Health Emergencies, urgent public health staffing shortages, crisis responses, National Special Security Events, and Global Health Events. Deployment is a collective responsibility for all public health officers. The Readiness and Deployment Branch (RDB) plays a critical role in ensuring that public health officers meet and comply with readiness requirements. These requirements are based on a policy-driven force health protection approach, encompassing physical, dental, and psychological examinations, along with mandatory investigations and vaccinations. Notably, noncombat-related injuries, gastrointestinal issues, dermatologic conditions, and respiratory disorders are the most common health concerns during deployment. While deployment is a crucial task, understanding its operational aspects, including the physical and mental well-being of public health officers, family readiness, and the consideration of ethical and cultural values, is of paramount importance. Maintaining readiness standards is vital for individual officers to effectively fulfill the mission of the commission corps. This article/presentation aims to cover the entire life cycle of a public health deployment assignment, shed light on family readiness for members facing deployment, explore ethical and cultural values encountered during deployment, identify essential skill sets for deployment, emphasize the importance of mental health awareness and readiness, and provide insights into the benefits and lessons learned from deployment experiences. Keywords: Mental health awareness, Family, Deployment, medical readiness, Public Health, Culture, Ethics. References Aoun O, Sanders JW, Hickey P. The Deployed Military: Medical Readiness and Travel-Related Health Issues. Travel Medicine. 2019:341–6. doi: 10.1016/B978-0-323-54696-6.00036-7. Epub 2018 Nov 26. PMCID: PMC7184237. Richard L. Griffith, Constanze Dostal, Nicholas A. Moon & Dominic Fedele (2023) The COVID-19 pandemic and the military: Lessons learned for readiness and resilience, Military Psychology, 35:5, 377-382, DOI: 10.1080/08995605.2023.2237392