The Traumatic Brain Injury Center of Excellences (TBICoE) unifies a system of traumatic brain injury health care across the Defense Health Agency, reliably advances the state-of-the-science for the warfighter and is always ready to meet future brain health challenges. To accomplish the mission, TBICoE supports, trains, and monitors service members, veterans, family members, and providers who have been, or care for those who are affected by a brain injury. Traumatic brain injury (TBI) is a significant health issue which affects service members, veterans, and their families during times of both conflict and peace (DOD Worldwide Numbers for TBI, 2024). Service members can sustain a TBI during routine activities, such as while playing sports or participating in recreational events, military training exercises and military deployment. Since 2000, about 82% of all TBIs documented in the military are concussions, also known as mild TBI (mTBI). In fact, most TBIs sustained by members of the United States Armed Forces are classified as mild (DOD Worldwide Numbers for TBI, 2024). The purpose of this poster is to provide an overview of the work being done by the Department of Defense (DOD) TBICoE to address policies written to support the evolving needs of the warfighter. Such policies include lines of effort outlined in the Warfighter Brain Health Initiative Strategy and Action Plan, as well as DOD policies related to the detection and management of traumatic brain injury. Specifically, we focus on the policies supporting the 2021 DOD Clinical Recommendation for the Progressive Return to Activity Following Acute Concussion/mTBI (TBICoE, 2021) and how knowledge translated through evidence-based research allows for application to clinical and operational settings. We overview the process being undertaken to deliver evidence-based clinical products to stakeholders across the Defense Health Agency, as well as the challenges and solutions, and provide examples of how Implementation Science can be used to optimize meaningful changes in service member care. We underscore the need to build a more solid foundation allowing for stronger relationships with more direct communication between stakeholders, researchers, and policymakers. Specific topics we address include: 1) A review of the impact of implementation science on addressing concussion management in service members; 2) exploring the application of knowledge translation principles, with a focus on challenges and their solutions that impact the transition of evidence into practice; 3) the use of Implementation Science principles at TBICoE to provide guidance on how to analyze the ability of interventions and policies to work (or not) in the real world treatment setting; and 4) the unique abilities and assets of TBICoE to translate research evidence into practice in order to meet the needs of the Military Health System (MHS).