Introduction “We have to be ready for war by 2029,” warned German Defense Minister Boris Pistorius. The time of peace in Europe is over, at the latest with the Russian Federation's attack on Ukraine, which violates international law. Therefore, Germany’s goal must also be “to provide deterrence in order to prevent the worst from happening.” [„Osnabrücker Erlass“, 04-30-2024]. Associated with this “turning point” (German Chancellor Scholz, speech on February 24, 2022, the day the war began in Ukraine), the term “resilience” is also coming into focus. Being resilient means having resilience and emerging stronger from threatening situations. What matters here is not just the individual, but also the surrounding group and even society as a whole. Due to its exceptional importance for the military, many NATO member states are already successfully implementing specific resilience programmes. „Resilient in Mission. Healthy in Life.“ The scientific orientation of the InstPrävMedBw The InstPrävMedBw is scientifically orientated precisely to the needs of our soldiers. With our investigations, we promote and create the conditions for sustainable health and resilience as a basis for the performance and resilience of the armed forces - an indispensable defense-relevant aspect! The InstPrävMedBw is a central federal departmental research institution and combines a wide variety of scientific disciplines with the archiving and analysis of health-related data from the entire Bundeswehr. Only this special constellation enables a unique science-based service, namely data-based [troop-related], evident results that can be made available to the military leadership as a control element in line with requirements. Current resilience research at the InstPrävMedBw The term “resilience” was originally used in materials science and describes the material property of returning to its original state after a changing force has been applied. Transferred to the human psyche, resilience means the ability of people or communities to survive and grow from difficult situations such as crises or disasters without permanent impairment. The ongoing research activities on the topic of resilience at the InstPrävMedBw currently extend to four areas: (I) scientific support of a resilience training for managers at the Center for Internal Leadership and a resilience training for nursing staff at the Psychotrauma Center Berlin, (II) cooperation with the German Army and the University of the Bundeswehr in Hamburg on resilience in basic training, (III) a joint research project with the Walter Reed Army Institute of Research, Maryland, USA and (IV) future studies on resilience research using biomarkers, including with the University of Giessen and brain research with the Leibniz-Institute for Resilience research in Mainz. Research area IV in particular harbours great potential because, according to current knowledge, the ability to not only to withstand stress but also to emerge stronger from stress is based on appropriate biological adaptation. The concentration of the body's own neuroendocrine, inflammatory and growth-stimulating substances can thus provide information about the extent of resilience. It is becoming increasingly clear that it is cheaper to examine a biomarker panel.