Long COVID is an infection-associated chronic condition (IACC) that occurs after SARS-CoV-2 infection and is present for at least 3 months as a continuous, relapsing and remitting, or progressive disease state. There are over 200 different symptoms of Long COVID, but fatigue, post exertional malaise and cognitive difficulties, or brain fog, are commonly reported. The Centers for Disease Control and Prevention estimates that about 3.4% of American adults are currently experiencing Long COVID and about 25% of adults with Long COVID report that they experience severe activity limitations. Despite the high prevalence of Long COVID, there is low public awareness of what Long COVID is, especially among communities of color and tribal communities. This lack of awareness can lead to challenges in health-related decision making, especially among those individuals who are experiencing long term symptoms of Long COVID that are not yet explained by a diagnosis. This lack of awareness can extend to healthcare providers as well, as Long COVID is a relatively new condition and there are limited clinician education resources available. The impact of Long COVID extends beyond health issues to significantly affect the workforce. Research has documented its effects on employment, and economists have projected a substantial economic impact through direct medical costs and lost productivity. This impact on the economy and workforce can be lessened though the provision of workplace accommodations. To address these issues, the U.S. Department of Health and Human Services (HHS), Office of the Assistant Secretary for Health (OASH) established the Office of Long COVID Research and Practice (OLC) to spearhead the whole-of-government response and coordinate federal efforts in both research and in delivery of supports and services across fourteen departments. The office is committed to reducing the impacts of Long COVID on people in the United States by advancing Long COVID research, strengthening clinical practice, offering services and supports, increasing public education, and coordination. External communications play a critical role in advancing this work and helping improve experiences for people living with Long COVID and the workforce. To ensure consistent communication among diverse stakeholders when discussing Long COVID, HHS commissioned the National Academies of Sciences, Engineering, and Medicine to conduct a comprehensive review of the evidence and establish a clear, unified definition of Long COVID. This definition reflects the experience of patients with Long COVID, the current state of research and the immediate needs of communities as we develop diagnostic methods and advance treatment strategies for both current and future patient care. Partnering with media helps ensure Long COVID gets the attention it deserves by raising awareness, combatting misinformation, and speaking with consistent terminology. Media partnerships can also increase funding support, encourage research, and advance policy to help improve experiences of patients and workforce. HHS communication efforts seek to advance policy efforts, increase funding support, and establish more resources for health care providers and employers. HHS is committed to helping patients and the workforce flourish as it addresses the challenges of Long COVID.