Burns, open wounds, and penetrating shrapnel injuries from combat blasts result in immense pain and prolonged recovery, delaying soldiers' return to duty(1). In Ukraine, hospitals are overwhelmed with a continuous influx of seriously wounded soldiers, facing over 30,000 new injuries each month(2). Effective wound management is crucial in this context. This case series evaluated the efficacy of a commercially available, shelf-stable, extended-wear transforming powder dressing (TPD), recently introduced at a Ukrainian combat hospital for treating acute traumatic wounds. Conventional wound care products often necessitate multiple dressing changes per day or week, consuming significant medical resources, including time, personnel, and materials. In contrast, TPD offers an innovative solution that can stay in place for extended periods (up to 30 days), potentially easing the burden on medical facilities and personnel. Four male soldiers (ages 28-51) with different types of injuries were treated with TPD: 1) mixed deep and superficial partial-thickness burns to 6% total body surface area (TBSA) on the back, neck, and arm, 2) embedded shrapnel wounds to the arm requiring necrotomy, 3) a shrapnel wound to the thigh complicated by hematoma and necrosis requiring surgical debridement, and 4) a penetrating wound to the buttock with embedded shrapnel. All patients received standard care with antibiotics and analgesics, and TPD was applied in place of conventional dressings. Upon hydration with wound exudate or saline, TPD aggregates to form a moist, oxygen-permeable barrier that protects the wound from contamination and supports healing by allowing vapor transpiration of excess fluids. Simple secondary covers may be used in areas of high exudation of friction. One of the key advantages of TPD is its ability to be topped off by simply sprinkling additional powder over the existing dressing, without the need for removing or changing the primary dressing layer. This feature makes it particularly useful in difficult to dress wounds, where frequent dressing changes are typically required with conventional products. As the wound heals, TPD dries and flakes off. In all four cases, the TPD was successfully used by the surgical team and the soldiers themselves during their recovery, including after discharge from the hospital. The soldiers reported a significant reduction in wound-related pain. The use of TPD also facilitated earlier discharge from the hospital (than anticipated for patients receiving conventional wound care treatments), as the wounds continued to heal effectively and were easily managed in combat conditions, reducing the frequency of dressing changes. Throughout the treatment, no complications were observed, and all wounds progressed to complete healing. This case series suggests that TPD is a valuable option for managing acute traumatic wounds in high-volume combat settings or civilian settings with a shortage of medical personnel. By providing effective wound coverage, reducing pain, minimizing the need for frequent dressing changes, and shortening hospital stays, TPD can play a critical role in conserving medical resources and improving patient outcomes in challenging environments.